|
KMID : 0613820230330010091
|
|
Journal of Life Science
2023 Volume.33 No. 1 p.91 ~ p.101
|
|
|
Biochemical Properties and Application of Bacteriocins Derived from Genus Bacillus
|
|
Lee Ji-Young
Kang Dae-Ook
|
|
|
Abstract
|
|
|
Bacteriocins are antimicrobial peptides synthesized on ribosomes, produced by bacteria, that inhibit the growth of similar or closely related bacterial strains. Since the discovery of nisin, many bacteriocins with unique structures and various modes of antibacterial activity have been described, and genes encoding production, secretion, and immunity have been reported. Nisin is one of the bacteriocins applied in cheese, liquid eggs, sauces and canned foods. Many of the bacteriocins of the genus Bacillus belong to lantibiotics, which are modified peptides after translation. Other genus Bacillus also produce many non-lantibiotic bacteriocins. Bacteriocins of the genus Bacillus are sometimes becoming more
important because of their broader antibacterial spectrum. Bacteriocins are considered attractive com- pounds in the food and pharmaceutical industries to prevent food spoilage and growth of pathogenic bacteria. Bacteriocins can be used as biological preservatives in a variety of ways in the food system. Biopreservation refers to extending shelf life and improving safety of foods using microorganisms and/or their metabolites. The demand for new antimicrobial compounds has generated great interest in new technologies that can improve food microbiological safety. Applications of bacteriocins are
expanding from food to human health. Today, many researchers are shifting their interest in bacteriocins
from food preservation to the treatment of bacteria that cause infections and antibiotic-resistant diseases. This exciting new era in bacteriocin research will undoubtedly lead to new inventions and new applications. In this review, we summarize the various properties and applications of bacteriocins produced by the genus Bacillus.
|
|
|
KEYWORD
|
|
|
Bacillus, bacteriocin, classificatioinL, lantibiotics, Listeria
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|